CAS NO: | 921099-13-0 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
生物活性 | TM-1 is a potent inhibitor ofpyruvate dehydrogenase kinase(PDHK1). TM-1 inhibitsPDHK1andPDHK2withIC50s of 2.97 μM and 5.2 μM, respectively. TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation, and inhibits cell proliferation[1]. | ||||||||||||
IC50& Target | IC50: 2.97 μM (PDK1), 5.2 μM (PDK2)[1] | ||||||||||||
体外研究 (In Vitro) | TM-1 (0-10 μM) inhibits PDHK1 activity with the inhibition rate of 80.5% (dosage at 10 μM) and an IC50value of 2.97 μM[1]. Cell Viability Assay[1]
| ||||||||||||
分子量 | 468.54 | ||||||||||||
性状 | Solid | ||||||||||||
Formula | C26H32N2O6 | ||||||||||||
CAS 号 | 921099-13-0 | ||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 |
|