CAS NO: | 1380548-02-6 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | SR10067 is a potent, selective and brain penetrantREV-ERBagonist. SR10067 has high affinity for Rev-Erbβ and Rev-Erbα withIC50values of 160 nM and 170 nM, respectively. SR10067 can be used for the research of metabolic diseases and neuropsychiatric disorders[1][2]. | ||||||||||||||||
IC50& Target | IC50: 160 nM (Rev-Erbβ); 170 nM (Rev-Erbα)[1] | ||||||||||||||||
体外研究 (In Vitro) | SR10067 has high affinity for Rev-Erbβ and Rev-Erbαwith IC50values are 160 and 170 nM, respectively[1]. | ||||||||||||||||
体内研究 (In Vivo) | SR10067 (i.p.; 30 mg/kg) has good pharmacokinetic properties in mouse[1].
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分子量 | 465.58 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C31H31NO3 | ||||||||||||||||
CAS 号 | 1380548-02-6 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL(214.79 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |