Rilmenidine-d4 is the deuterium labeled Rilmenidine. Rilmenidine, an innovative antihypertensive agent, is an orally active, selectiveI1imidazoline receptoragonist. Rilmenidine is analpha 2-adrenoceptoragonist. Rilmenidine inducesautophagy. Rilmenidine acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na⁺/H⁺antiport. Rilmenidine modulates proliferation and stimulates the proapoptotic proteinBaxthus inducing the perturbation of the mitochondrial pathway andapoptosisin human leukemic K562 cells^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

184.27

C₁₀H₁₂D₄N₂O

85047-14-9

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.