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Licochalcone D
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Licochalcone D图片
CAS NO:144506-15-0
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Licochalcone D 是存在于Glycyrrhiza inflate 中的黄酮类化合物,是NF-κB p65 的有效抑制剂。Licochalcone D 具有抗氧化、抗炎、抗癌等作用。
Cas No.144506-15-0
别名甘草查尔酮 D
Canonical SMILESO=C(C1=CC=C(O)C(C/C=C(C)\C)=C1)/C=C/C2=CC=C(O)C(O)=C2OC
分子式C21H22O5
分子量354.4
溶解度DMSO: 125 mg/mL (352.71 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza inflate, is a potent inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2]. p65

[1]. Furusawa J, et al. Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol. 2009 Apr;9(4):499-507. [2]. Si L, et al. Licochalcone D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells. Oncol Rep. 2018 May;39(5):2160-2170.