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diABZI STING agonist-1 Tautomerism
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
diABZI STING agonist-1 Tautomerism图片
CAS NO:2138498-18-5
包装与价格：
包装价格(元)
250mg电议
500mg电议

产品介绍
diABZI STING agonist-1 (Tautomerism) 是一个选择性的干扰素基因刺激受体 (STING) 的激动剂，其在人中的 EC50 值为 130 nM。
Cas No.2138498-18-5
Canonical SMILESO=C(N)C1=CC(N/C(N2C/C=C/CN3/C(NC4=C3C(OCCCN5CCOCC5)=CC(C(N)=O)=C4)=N/C(C6=CC(C)=NN6CC)=O)=N\C(C7=CC(C)=NN7CC)=O)=C2C(OC)=C1
分子式C42H51N13O7
分子量849.94
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs. EC50: 130 nM (human STNG in PBMCs) [1].

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. At a concentration of 1 μM, diABZI STING agonist-1 (compound 3) demonstrates high selectivity against more than 350 kinases tested[1].

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.