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diABZI STING agonist-1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
diABZI STING agonist-1图片
CAS NO:2138299-33-7
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
diABZI STING agonist-1 是一个选择性的干扰素基因刺激受体 (STING) 的激动剂。
Cas No.2138299-33-7
Canonical SMILESO=C(N)C1=CC(N=C(NC(C2=CC(C)=NN2CC)=O)N3C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCN7CCOCC7)=CC(C(N)=O)=C6)=C3C(OC)=C1
分子式C42H51N13O7
分子量849.94
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist. STING[1].

diABZI STING agonist-1 activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting-/- mice, confirming that diABZI STING agonist-1 induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.