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(S)-(+)-3-Quinuclidinol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(S)-(+)-3-Quinuclidinol图片
CAS NO:34583-34-1
包装与价格:
包装价格(元)
500mg电议
1g电议
5g电议

产品介绍
(S)-(+)-Quinuclidinol is a precursor in the synthesis of solifenacin.
Cas No.34583-34-1
别名(S)-(+)-3-喹宁醇
Canonical SMILESO[C@H]1C2CCN(CC2)C1
分子式C7H13NO
分子量127.2
溶解度DMF: 16.7 mg/ml,DMSO: 12.5 mg/ml,Ethanol: 33.3 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S)-(+)-Quinuclidinol is a precursor in the synthesis of solifenacin . Solifenacin is a competitive antagonist of muscarinic receptors that potently blocks signaling through M1, M2, and M3 (Kis = 25, 125, and 10 nM, respectively). Through this action, solifenacin prevents activation by acetylcholine, resulting in muscle relaxation. Formulations containing solifenacin have been used in the management of overactive bladder, as it reduces the number of micturition, urgency, and incontinence episodes.