CAS NO: | 34583-34-1 |
包装 | 价格(元) |
500mg | 电议 |
1g | 电议 |
5g | 电议 |
Cas No. | 34583-34-1 |
别名 | (S)-(+)-3-喹宁醇 |
Canonical SMILES | O[C@H]1C2CCN(CC2)C1 |
分子式 | C7H13NO |
分子量 | 127.2 |
溶解度 | DMF: 16.7 mg/ml,DMSO: 12.5 mg/ml,Ethanol: 33.3 mg/ml,PBS (pH 7.2): 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | (S)-(+)-Quinuclidinol is a precursor in the synthesis of solifenacin . Solifenacin is a competitive antagonist of muscarinic receptors that potently blocks signaling through M1, M2, and M3 (Kis = 25, 125, and 10 nM, respectively). Through this action, solifenacin prevents activation by acetylcholine, resulting in muscle relaxation. Formulations containing solifenacin have been used in the management of overactive bladder, as it reduces the number of micturition, urgency, and incontinence episodes. |