CAS NO: | 2552-55-8 |
包装: | 5mg |
市场价: | 1890元 |
Cas No. | 2552-55-8 |
别名 | 鹅膏氨酸,(RS)-Ibotenic acid; DL-Ibotenic acid |
化学名 | (S)-2-amino-2-(3-oxo-2,3-dihydroisoxazol-5-yl)acetic acid |
Canonical SMILES | OC([C@H](C(ON1)=CC1=O)N)=O |
分子式 | C5H6N2O4 |
分子量 | 158.11 |
溶解度 | Water: 10mM |
储存条件 | Desiccate at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites. Ibotenic acid (Ibo) is capable of acting at both NMDA and trans-ACPD receptors in the CNS, although only activation of NMDA receptors is involved in Ibo neurotoxicity. Ibotenic acid is toxic to cortical neurons exposes for 5 min with an EC50=77.3±8 μM (n=5) as measured by release of lactate dehydrogenase to the culture media[1]. References: |