Tiagabine (NO050328) 是一种有效的选择性 GABA 再摄取抑制剂,用作抗惊厥药,在突触体、神经元和神经胶质细胞中摄取 [3H]GABA 的 IC50 分别为 67、446 和 182 nM。
Cas No. | 115103-54-3 |
别名 | 噻加宾 |
化学名 | (R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl)piperidine-3-carboxylic acid |
Canonical SMILES | CC(C=CS1)=C1/C(C2=C(C=CS2)C)=C/CCN3CCC[C@](C(O)=O)([H])C3 |
分子式 | C20H25NO2S2 |
分子量 | 375.55 |
溶解度 | ≥ 13.5mg/mL in Water |
储存条件 | Store at 2-8°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |