Ac-DEVD-AMC is theCaspase-3fluorescent substrate.

Ac-DEVD-AMC is the caspase-3 substrate and could be used to monitor intracellular caspase-3 activity^[1].
The AMC moiety is highest at 2 h (area =5.6±1.8), the AMC peak area for Ac-DEVD-AMC incubated without lung specimen (substrate alone) for 6 h is relatively small^[2].

675.64

Solid

C₃₀H₃₇N₅O₁₃

169332-61-0

N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin

Ac-DEVD-7-amido-4-Methylcoumarin

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

H₂O : 0.67 mg/mL(0.99 mM;Need ultrasonic)

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

• 1.

  请依序添加每种溶剂： PBS

  Solubility: 3.33 mg/mL (4.93 mM); Clear solution; Need ultrasonic