CAS NO: | 201608-14-2 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm). | ||||||||||||||||
体外研究 (In Vitro) | After incubation with Ac-DEVD-AFC for 1 hour, significant increase of caspase-3 activity is observed at 4 hour compare with control. There are no significant increases of caspase-3 activity in Photofrin and LPLI group. The cleavage of Ac-DEVD-AFC in response to caspase-3 activation is remarkably inhibited by shRNA-BimL transfection[1]. | ||||||||||||||||
分子量 | 729.61 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C30H34F3N5O13 | ||||||||||||||||
CAS 号 | 201608-14-2 | ||||||||||||||||
Emission (Em) | Em 450-495 nm Blue | ||||||||||||||||
Sequence | N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoroMethylcoumarin | ||||||||||||||||
Sequence Shortening | Ac-DEVD-7-amido-4-trifluoroMethylcoumarin | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : ≥ 50 mg/mL(68.53 mM) H2O :< 0.1 mg/mL(insoluble) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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