Ampicillin

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Ampicillin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

69-53-4

包装与价格：

包装	价格(元)
10 mM * 1 mL in Water	电议
500mg	电议
1 g	电议
5 g	电议
10 g	电议
50 g	电议

产品名称

氨苄青霉素
D-(-)-α-Aminobenzylpenicillin

产品介绍

Ampicillin是一种广谱β-内酰胺抗生素，适用于各种革兰氏阳性和革兰氏阴性菌。

生物活性

Ampicillin is a broad-spectrum beta-lactamantibioticagainst a variety of gram-positive and gram-negative bacteria.

IC₅₀& Target

β-lactam

体外研究
(In Vitro)

Ampicillin inhibits the growth ofE. coliof swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL^[1].

体内研究
(In Vivo)

Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig^[1]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood^[2]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia^[3].

Clinical Trial

分子量

349.40

性状

Solid

Formula

C₁₆H₁₉N₃O₄S

CAS 号

69-53-4

中文名称

氨苄西林；氨苄青霉素；阿苄西林；胺苄青霉素；氨苄青；安比西林；氨必西林

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

0.1 M NaOH : 25 mg/mL(71.55 mM;Need ultrasonic)

H₂O : 5 mg/mL(14.31 mM;ultrasonic and warming and heat to 60℃)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	2.8620 mL	14.3102 mL	28.6205 mL
5 mM	0.5724 mL	2.8620 mL	5.7241 mL
10 mM	0.2862 mL	1.4310 mL	2.8620 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (protect from light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。