Chloroquine-d5 diphosphate is the deuterium labeled Chloroquine (phosphate). Chloroquine phosphate is anantimalarialand anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is anautophagyandtoll-like receptors (TLRs)inhibitor. Chloroquine phosphate is highly effective in the control ofSARS-CoV-2 (COVID-19)infectionin vitro (EC₅₀=1.13 μM)^[1][2][3][4].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

520.89

C₁₈H₂₇D₅ClN₃O₈P₂

1854126-42-3

磷酸氯喹 d5 (二磷酸盐)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.