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K252d
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
K252d图片
CAS NO:105114-22-5
包装:1mg
市场价:3916元

产品介绍
A PKC inhibitor
Cas No.105114-22-5
Canonical SMILESO=C1NCC2=C1C(C(C=CC=C3)=C3N4[C@@]5([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)=C4C6=C2C7=C(C=CC=C7)N6
分子式C26H23N3O5
分子量457.5
溶解度DMSO: soluble,Ethanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

K252d is an indolocarbazole alkaloid found inNocardiopsis.1It is a PKC inhibitor that inhibits PKC isolated from rat brain (IC50= 350 nM). It also inhibits calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart (IC50= 46.2 µM).

1.Nakanishi, S., Matsuda, Y., Iwahashi, K., et al.K-252b, c and d, potent inhibitors of protein kinase C from microbial originJ. Antibiot. (Tokyo) 39(8)1066-1071(1986)