Laminaran

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Laminaran

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

9008-22-4

包装与价格：

包装	价格(元)
100mg	电议
200mg	电议
500mg	电议

产品介绍

Laminaran 是一种中性水溶性 β-1-3-葡聚糖，从褐藻双歧杆菌中分离，Dectin-1 的典型配体，具有强大的免疫调节，辐射防护作用，以及抗癌活性。 Laminaran 由具有 β (1→6) 分支的 β (1→3)-葡聚糖组成，可以被葡糖酶诸如 (EC 3.2.1.6) 之类的酶催化，该酶会破坏 β (1→3) 键。 Laminaran 是一种有前途的免疫刺激分子，可用于癌症免疫治疗。

Cas No.	9008-22-4
别名	昆布多糖
Canonical SMILES	OC[C@H]1OC(O[C@H]2[C@H](O)[C@@H](CO)OC(O[C@@H]3[C@@H](O)C(O[H])O[C@H](CO)[C@H]3O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O.[n]
溶解度	DMSO: 100 mg/mL; Water: 100 mg/mL
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Laminaran is a neutral water-soluble β-1-3-glucan and a typical ligand for Dectin-1 isolated from the brown alga D. dichotoma, has potent immunomodulating, radioprotective, and anticancer activities[1]. Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds[2]. Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy[3]. [1]. Malyarenko OS, et al. Laminaran from brown alga Dictyota dichotoma and its sulfated derivative as radioprotectors and radiosensitizers in melanoma therapy.Carbohydr Polym. 2019 Feb 15;206:539-547. [2]. Laminaran [3]. Song K, et al. Laminarin promotes anti-cancer immunity by the maturation of dendritic cells.Oncotarget. 2017 Jun 13;8(24):38554-38567.