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Coenzyme B12
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Coenzyme B12图片
CAS NO:13870-90-1
包装与价格:
包装价格(元)
25mg电议
100mg电议

产品介绍
辅酶 B12 (Coenzyme B12;Cobamamide;AdoCbl) 是维生素 B12 的一种活性形式,它是甲基丙二酰辅酶 A 变位酶 [1] 的辅助因子:辅酶 B12 是一组催化异常重排或消除反应的酶的辅助因子。
Cas No.13870-90-1
别名腺苷钴胺; Coenzyme B12; Cobamamide; AdoCbl
Canonical SMILESO[C@@H]1[C@H](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]1O)[CH2-][Co+3]456([N]7=CN([C@]8([H])[C@H](O)[C@H](O9)[C@@H](CO)O8)C%10=CC(C)=C(C)C=C7%10)[N]%11=C%12[C@@H](CCC(N)=O)[C@@](CC(N)=O)(C)[C@]%11(C)[C@]([C@H](CC(N)=O)[C@]%13(CCC(NC[C@@H](C)O[P]9([O-])=O)=
分子式C72H100CoN18O17P
分子量1579.6
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Coenzyme B12 (adenosylcobalamin; AdoCbl) is a biologically active form of vitamin B12 . It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced only by certain bacteria and archaea. It is a cofactor for various enzymes including mutases, eliminases, aminomutases, and a reductase. These enzymes catalyze reactions that generate free radicals through release of the adenosyl group, allowing usually unreactive molecules to become reactive. Only one of these enzymes, methylmalonyl CoA mutase, is found in mammals, therefore, the other enzymes must be taken in through the diet. Genetic mutations in enzymes that synthesize AdoCbl lead to AdoCbl deficiency and methylmalonic aciduria. Formulations containing AdoCbl are used to treat patients with this disorder.