CAS NO: | 328898-40-4 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
2mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Tildipirosin, a long-actingmacrolide, hasantibioticactivity. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Tildipirosin exhibits the inhibitory effect onC. colispecies, and 23 of 31 (74%) isolates have MICs of 8 or 16 μg/mL while 8 of 31 (26%) have MIC >256 μg/mL. MICs against C.jejuniare 8-64 μg/mL. Tildipirosin againstS. entericaandE. coliare 2-8 μg/mL[1]. Tildipirosin inhibits the treponeme isolates form from CODD lesions from 19 sheep, with MIC90 of 0.0469 mg/L[3]. TheP. multocidaB130 clones show the MIC of 0.25 mg/L for tildipirosin. The 10P. multocidaisolates that carry only erm(42) exhibit MIC of 16-32 mg/L for tildipirosin. The singleM. haemolyticathat harbours only erm(42) shows MIC of 32 mg/L for tildipirosin[4]. | ||||||||||||||||
体内研究 (In Vivo) | The mean percentage of lung consolidation for tildipirosin (4 mg/kg, s.c.)-treated calves is significantly lower than those for tulathromycin-treated and control calves. Metaphylactic administration of tildipirosin to calves 5 days prior to H somni challenge prevents subsequent culture of the pathogen from bronchial secretions and is more effective in minimizing clinical disease and lung lesions than is metaphylactic administration of tulathromycin[2]. | ||||||||||||||||
分子量 | 734.02 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C41H71N3O8 | ||||||||||||||||
CAS 号 | 328898-40-4 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : ≥ 100 mg/mL(136.24 mM) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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