CAS NO: | 6153-64-6 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Oxytetracycline dihydrate is anantibioticbelonging to thetetracyclineclass. Oxytetracycline dihydrate potent inhibitsGram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is aprotein synthesisinhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1activity[1][2][3]. | ||||
IC50& Target[1][3] |
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体外研究 (In Vitro) | Oxytetracycline is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products. Oxytetracycline is synthesized by a type II polyketide synthase that generates the poly-beta-ketone backbone through successive decarboxylative condensation of malonyl-CoA extender units, followed by modifications by cyclases, oxygenases, transferases, and additional tailoring enzymes[2]. | ||||
体内研究 (In Vivo) | The effects of administration a therapeutic dose of Oxytetracycline (82.8 mg/kg of bw to 1 % bw/day) for 10 days are species specific. Oxytetracycline increases the relative liver weight inMorone chrysops x M. saxatilis, the enzymatic activity of CYP3A4 in Ictalurus punctatus, protein expression of CYP3A4 in Oreochromis niloticus and depleted the hepatic CYP3A4 in the latter[1]. | ||||
分子量 | 496.46 | ||||
Formula | C22H28N2O11 | ||||
CAS 号 | 6153-64-6 | ||||
中文名称 | 土霉素二水合物;地霉素二水合物;氧四环素二水合物 | ||||
结构分类 |
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来源 | Streptomyces rimosus | ||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |