Anti-MRSA agent 5 (B14) is a potent
MRSA
agent withMIC₅₀values of 0.38 μg/mL and has low hERG activity with anIC₅₀values of >40 μM. Anti-MRSA agent 5 (B14) also has low cytotoxicity to mammal cells and unlikely to acquirebacterialresistance^[1].

MIC: 0.38 μg/mL (MRSA); IC50: >40 Μm (hERG)

Anti-MRSA agent 5 (B14) is highly selective toxic in bacterial cells. Anti-MRSA agent has marginal inhibitory activities with anIC₅₀values of exceeding 40 μM. Anti-MRSA agent 5 (B14) has strong antibacterial activity for all five clinical isolates of MRSA (NRS-1, NRS-70, NRS-100, NRS-108, NRS-271) with MIC values between< 0.17 and 0.69 μg/mL.Anti-MRSA agent 5 (B14) inhibits all three clinical isolates of fluoroquinolone-resistant MRSA (19-25, 19-26, 19-27) and exhibits good potency against VISA^[1].

442.47

C₂₅H₂₂N₄O₄

2490154-44-2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.