Aurapten 是天然存在的最丰富的香叶氧基香豆素。
| Cas No. | 495-02-3 |
| 别名 | 橙皮油素 |
| Canonical SMILES | O=C1C=CC2=C(C=C(OC/C=C(C)/CC/C=C(C)\C)C=C2)O1 |
| 分子式 | C19H22O3 |
| 分子量 | 298.4 |
| 溶解度 | DMF: 14 mg/ml,DMF:PBS(pH7.2) (1:2): 0.3 mg/ml,DMSO: 12 mg/ml,Ethanol: 12 mg/ml |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis. When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM. |
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