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ADT-OH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ADT-OH图片
CAS NO:18274-81-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
ADT-OH 是一种释放硫化氢的供体。 ADT-OH 通过上调 FADD 诱导细胞凋亡并抑制体内黑色素瘤的发展。 ADT-OH具有研究癌症疾病的潜力。
Cas No.18274-81-2
别名5-(4-羟基苯基)-3H-1,2-二硫杂环戊烯-3-硫酮,5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1
Canonical SMILESOC1=CC=C(C2=CC(SS2)=S)C=C1
分子式C9H6OS3
分子量226.3
溶解度DMF: 15 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 5 mg/ml,Ethanol: 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. It can be readily esterified with other moieties. For example, it can be coupled with therapeutics like nonsteroidal anti-inflammatory drugs, as in the generation of ATB-343 . ADT-OH has also been linked with a mitochondria-targeting motif to produce AP-39 , which selectively increases mitochondrial H2S levels. ADT-OH is used both in cells and in animals for comparative studies with derived chimeras.