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1'-hydroxy Midazolam
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1'-hydroxy Midazolam图片
CAS NO:59468-90-5
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
1'-羟基咪达唑仑是咪达唑仑的主要活性代谢物,是一种神经元抑制剂。
Cas No.59468-90-5
别名1-羟基咪达唑仑
化学名8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-methanol
Canonical SMILESFC1=CC=CC=C1C2=NCC3=CN=C(CO)N3C4=C2C=C(Cl)C=C4
分子式C18H13ClFN3O
分子量341.8
溶解度1 mg/ml DMSO, 2 mg/ml in DMF
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1’-hydroxy Midazolam is the major metabolite of the anesthetic, midazolam. It is produced rapidly by the actions of hepatic cytochrome P450 3A and has been shown to be equipotent to midazolam.[1]

Reference:
[1]. Perloff, M.D., Von Moltke, L.L., Court, M.H., et al. Midazolam and triazolam biotransformation in mouse and human liver microsomes: Relative contribution of CYP3A and CYP2C isoforms. Journal of Pharmacology and Experimental Therapeutics 292(2), 618-628 (2016).