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Carbosulfan
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Carbosulfan图片
CAS NO:55285-14-8
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议
500mg电议

产品介绍
Carbosulfan强效抑制CYP3A4,适度抑制CYP1A1/2和CYP2C19。
Cas No.55285-14-8
别名丁硫克百威
Canonical SMILESO=C(OC1=C(OC(C)(C)C2)C2=CC=C1)N(SN(CCCC)CCCC)C
分子式C20H32N2O3S
分子量380.54
溶解度DMSO : ≥ 68 mg/mL (178.69 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carbosulfan inhibited relatively potently CYP3A4 and moderately CYP1A1/2 and CYP2C19 in pooled HLM (human livers). Carbosulfan activation is predominantly catalyzed in humans by CYP3A4.

[1]. Abass K, et al. Metabolism of carbosulfan II. Human interindividual variability in its in vitro hepatic biotransformation and the identification of the cytochrome P450 isoforms involved. Chem Biol Interact. 2010 May 14;185(3):163-173.