硫代半乳糖苷 (TDG) 是一种口服有效的半乳凝素 (GAL) 抑制剂，对 GAL1 和 GAL3 的 Kd 值分别为 24 μM 和 49 μM 。
| Cas No. | 51555-87-4 |
| 别名 | D-吡喃半乳糖Β-D-硫代吡喃半乳糖苷,TDG |
| Canonical SMILES | O[C@@H]1[C@H](O)[C@@H](O)[C@H](S[C@@]2([H])[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)O[C@@H]1CO |
| 分子式 | C12H22O10S |
| 分子量 | 358.4 |
| 溶解度 | DMF: 1 mg/ml,DMSO: 20 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Galectins are a family of glycan-binding lectins with diverse regulatory roles in physiological processes. They have significant roles in inflammation and cancer. Thiodigalactoside is a diglycan that binds galectins-1, -3, -8, and -9 with Kd values between 24 and 78 µM. It is used to investigate the roles of these galectins in cell signaling and carcinogenesis. |
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