(-)-Catechin 是儿茶素的异构体，在手性中心具有反式 2S,3R 构型。儿茶素抑制 cyclooxygenase-1 (COX-1) 的 IC50 为 1.4 μM.
| Cas No. | 18829-70-4 |
| 别名 | (-)-儿茶素; (-)-Cianidanol; (-)-Catechuic acid |
| Canonical SMILES | OC1=CC2=C(C[C@@H](O)[C@H](C3=CC=C(O)C(O)=C3)O2)C(O)=C1 |
| 分子式 | C15H14O6 |
| 分子量 | 290.3 |
| 溶解度 | DMF: 25 mg/ml,DMSO: 15 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): 1 mg/ml |
| 储存条件 | 4°C, away from moisture and light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (-)-Catechin is a diastereoisomer of catechin having a trans 2S,3R configuration at the chiral center. Catechins, in general, are polyphenolic flavonoids that can be isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechins are potent antioxidants that inhibit the free radical-induced oxidation of isolated LDL by AAPH . Catechins and other related procyanidin compounds have antitumor activity when tested in a two-stage mouse epidermal carcinoma model employing topical application. |
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