| CAS NO: | 718612-49-8 |
| 包装: | 1mg |
| 市场价: | 14500元 |
| 生物活性 | SN-38-d3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of theTopoisomeraseIinhibitor Irinotecan. SN-38 (NK012) inhibitsDNAandRNA synthesiswithIC50s of 0.077 and 1.3 μM, respectively[1][2][3][4]. | |||||||||
| 体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. | |||||||||
| 分子量 | 395.42 | |||||||||
| 性状 | Solid | |||||||||
| Formula | C22H17D3N2O5 | |||||||||
| CAS 号 | 718612-49-8 | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 |
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