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Oxcarbazepine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oxcarbazepine图片
CAS NO:28721-07-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议

产品介绍
奥卡西平是一种钠通道阻滞剂。
Cas No.28721-07-5
别名奥卡西平; GP 47680
化学名5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide
Canonical SMILESC1C2=CC=CC=C2N(C3=CC=CC=C3C1=O)C(=O)N
分子式C15H12N2O2
分子量252.27
溶解度≥ 9.1mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Oxcarbazepine (GP 47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.

References:
[1]. May, T.W., E. Korn-Merker, and B. Rambeck, Clinical pharmacokinetics of oxcarbazepine. Clin Pharmacokinet, 2003. 42(12): p. 1023-42.