Maytansinoid DM4 is a thiol-containing maytansine derivative with highly potent cytotoxicity. Maytansinoid DM4 can be used as a cytotoxic moiety of ADC^[1][2].

Maytansine is a natural benzoansamacrolide product isolated from the bark of the African shrubMaytenus ovatus. Maytansine binds to the same site on tubulin as the vinca alkaloids, with similar in vitro inhibition constants, but is a more-potent cytotoxin^[1].

794.39

C₃₉H₅₆ClN₃O₁₀S

799840-96-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.