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Py-MPB-amino-C3-PBD
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Py-MPB-amino-C3-PBD图片
CAS NO:2412924-07-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Py-MPB-amino-C3-PBD 是一种细胞毒性药物,可作为 ADC 的有效载荷。具有抗微生物活性。
生物活性

Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Py-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1].

IC50& Target[1][1][1]

Pyrrolobenzodiazepines

 

体外研究
(In Vitro)

Py-MPB-amino-C3-PBD (compound 73) shows cytotoxicity with IC50s of 301, 144.1 and 37.5 nM for U138-MG, A431, and REH cells, respectively. Py-MPB-amino-C3-PBD possesses potent anti-bacterial effects against the gram negative strain E. coli K12, with potency of 2 pg/mL determined[1].

分子量

744.84

Formula

C41H44N8O6

CAS 号

2412924-07-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.