CAS NO: | 93908-02-2 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
生物活性 | Rebeccamycin, an antitumorantibiotic, inhibitsDNAtopoisomeraseI. Rebeccamycin appears to exert its primary antineoplastic effect by poisoningtopoisomeraseI and has negligible effect on protein kinase C andtopoisomeraseII[1][2]. | ||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | Rebeccamycin is an antitumor antibiotic produced by the actinomyceteSaccharotrix aerocolonigeneswith activity against several human tumor cell lines, including A549 (lung adenocarcinoma), HCT-116 (colon carcinoma), and KB (nasopharyngeal carcinoma)[1]. | ||||||||
体内研究 (In Vivo) | Rebeccamycin (2-256 mg/kg; i.p.; daily for 9 days) prolongs survival in B16 melanoma, L1210 leukemia[2].
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分子量 | 570.38 | ||||||||
Formula | C27H21Cl2N3O7 | ||||||||
CAS 号 | 93908-02-2 | ||||||||
结构分类 |
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来源 | the mycelium | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |