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Tubulysin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tubulysin A图片
CAS NO:205304-86-5
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
TubA
产品介绍
Tubulysin A(TubA)是黏液性细菌的产物,体外具有抗血管生成、抗有丝分裂、抗增殖的作用。
生物活性

Tubulysin A(TubA) is a myxobacterial product that can function as an antiangiogenic agent in many in vitro assays; anti-microtubule, anti-mitotic, anapoptosisinducer, anticancer, anti-angiogenic, and antiproliferative. IC50 value: Target: microtubule Tubulysin A is a novelantibiotic, which is anti-microtubule, anti-mitotic,apoptosisinducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins are cytotoxicpeptides, which include 9 members (A-I). Tubulysin A has potential application as an anticancer agent. It arrests cells in the G2/M phase. Tubulysin A inhibits polymerization more efficiently than vinblastine and induces depolymerization of isolated microtubules. Tubulysin A has potent cytostatic effects on various tumor cell lines with IC50 in the picomolar range.

IC50& Target

Traditional Cytotoxic Agents

 

分子量

844.07

Formula

C43H65N5O10S

CAS 号

205304-86-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.