您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > NH2-MPAA-NODA
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
NH2-MPAA-NODA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NH2-MPAA-NODA图片
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
NH2-MPAA-NODA 是一种基于硝基的可光裂解的linker,它有一个 NODA 修饰单元和一个 MPAA 主链。NH2-MPAA-NODA 可以通过标记18F-氟化物来用作放射性标签。
生物活性

NH2-MPAA-NODA is a nitroveratryl-based photocleavablelinker, it has a NODA motif and a methyl phenyl acetic acid (MPAA) backbone[1]. NH2-MPAA-NODA can be used as a radiolabel by labeling with18F-fluoride.

IC50& Target

IC50: Nitroveratryl-based photocleavable linker

体外研究
(In Vitro)

NH2-MPAA-NODA contains the 1,4,7-triazacyclononane-1,4-diacetate (NODA) motif with a methyl phenyl acetic acid (MPAA) backbone, and it has enough ability to form stable Al18F-chelates. The organ of luoroaluminates are easily accessible from the reaction of 1 and AlF3.
NH2-MPAA-NODA can be conjugated to some inhibitors/antagonists labeled with18F for PET imaging of targeting tumors. It also can be used as a radiolabel of peptides[1]

分子量

435.52

性状

Solid

Formula

C21H33N5O5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month