Bis-PEG6-NHS ester is a PEG-basedPROTAClinkercan be used in the synthesis ofPROTACs. Bis-PEG6-NHS ester is acleavableADC linkerused in the synthesis ofantibody-drug conjugates (ADCs)^[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

576.55

Viscous liquid

C₂₄H₃₆N₂O₁₄

1526718-98-8

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture

*该产品在溶液状态不稳定，建议您现用现配，即刻使用。

DMSO : 125 mg/mL(216.81 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。