m-PEG5-succinimidyl carbonate is anon-cleavable5 unit PEGADClinker used in the synthesis ofantibody-drug conjugates (ADCs). m-PEG5-succinimidyl carbonate is a PEG/Alkyl/ether-basedPROTAClinker can be used in the synthesis ofPROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

393.39

C₁₆H₂₇NO₁₀

1058691-00-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.