CAS NO: | 1807518-67-7 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
1 g | 电议 |
生物活性 | Bromoacetamido-PEG4-acid is a PEG-basedPROTAClinker that can be used in the synthesis ofPROTACs[1]. Bromoacetamido-PEG4-acid is also acleavable4 unit PEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs)[2]. | ||||||||||||
IC50& Target |
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体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2]. | ||||||||||||
分子量 | 386.24 | ||||||||||||
性状 | Viscous liquid | ||||||||||||
Formula | C13H24BrNO7 | ||||||||||||
CAS 号 | 1807518-67-7 | ||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 |
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