12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA).
| Cas No. | 72710-10-2 |
| Canonical SMILES | CCCCC/C=C\C[C@H](O)/C=C/C=C\CCCCCCC(O)=O |
| 分子式 | C20H34O3 |
| 分子量 | 322.5 |
| 溶解度 | 0.1 M Na2CO3: 2 mg/ml,DMF: Miseble,DMSO: Miseble,Ethanol: Miscible,PBS (pH 7.2): 0.8 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA). 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 µM), α granule secretion, integrin αIIbβ3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro. |
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