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Nocodazole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nocodazole图片
CAS NO:31430-18-9
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

Nocodazole是微管抑制剂;抑制有丝分裂。也抑制自噬体-溶酶体融合。

靶点信息

Microtubules (Cell-free assay)Abl (Cell-free assay)Abl (E255K) (Cell-free assay)Abl (T315I) (Cell-free assay)
N/A0.21 μM0.53 μM0.64 μM

化学数据

目录号A13219
作用机制Inhibitor (抑制剂)
M. Wt301.32
FormulaC14H11N3O3S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.31430-18-9
SMILESCOC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3

溶解度

In vitro (25°C)DMSO6 mg/mL (19.91 mM)
WaterInsoluble
EthanolInsoluble
In vivo2% DMSO+30% PEG 300+2% Tween 80+ddH2O1 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM33.19 mL165.94 mL331.87 mL
0.5 mM6.64 mL33.19 mL66.37 mL
1 mM3.32 mL16.59 mL33.19 mL
5 mM0.66 mL3.32 mL6.64 mL

*The above data is based on the productmolecular weight 301.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.