Mal-PEG2-Val-Cit-PAB-OH

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2055041-38-6

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Mal-PEG2-Val-Cit-PAB-OH 是一种可降解 (cleavable) 的ADC linker，用于抗体偶联药物 (ADCs) 的合成。 Mal-PEG2-Val-Cit-PAB-OH 也可用作 PROTAC 的 Linker，可用于 PROTAC 的合成。

生物活性

Mal-PEG2-Val-Cit-PAB-OH is acleavableADC linkerused in the synthesis ofantibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-PAB-OH also can be used as aPROTAClinkerthat can be used in the synthesis ofPROTACs.

IC₅₀& Target

Cleavable

Protease Cleavable

PEGs

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

分子量

618.68

Formula

C₂₉H₄₂N₆O₉

CAS 号

2055041-38-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.