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N-acetyl-D-Glucosamine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-acetyl-D-Glucosamine图片
CAS NO:7512-17-6
包装与价格：
包装价格(元)
500mg电议
1g电议
5g电议
10g电议

产品介绍

N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) 是葡萄糖的单糖衍生物。

Cas No.7512-17-6
别名N-乙酰-D-氨基葡萄糖; N-Acetyl-2-amino-2-deoxy-D-glucose
Canonical SMILESO=CC(NC(=O)C)C(O)C(O)[C@H](O)CO
分子式C8H15NO6
分子量221.2
溶解度≤10mg/ml in DMSO;0.25mg/ml in dimethyl formamide
储存条件Store at -20℃, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Levels of O-GlcNAcylation proteins from Alzheimer’s disease brain extracts are decreased as compared to that in controls, suggesting that release of GlcNAc may contribute to pathogenesis. In E. coli, GlcNAc induces the expression of multidrug exporter genes, indicating that this sugar can alter gene expression. GlcNAc is also the monomeric unit of chitin, which is found in fungi and many invertebrates, including crustaceans, insects, and nematodes. For this reason, chemicals that inhibit the incorporation of GlcNAc into chitin are cytotoxic to these organisms.