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Resolvin D1 methyl ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Resolvin D1 methyl ester图片
CAS NO:937738-63-1
包装与价格:
包装价格(元)
10μg电议
25μg电议
50μg电议
100μg电议

产品介绍
Resolvin D1 甲酯(RvD1 甲酯)是 Resolvin D1 的甲酯。
Cas No.937738-63-1
别名RvD1 methyl ester
Canonical SMILESCC/C=C\C[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)C/C=C\CCC(OC)=O
分子式C23H34O5
分子量390.5
溶解度DMF: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 0.05 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM. RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.