5(S),15(S)-DiHETE 是一种“活化”中间体，抑制血小板聚集，IC50 为 1.3 μM。
| Cas No. | 82200-87-1 |
| Canonical SMILES | CCCCC[C@H](O)/C=C/C=C\C/C=C\C=C\[C@@H](O)CCCC(O)=O |
| 分子式 | C20H32O4 |
| 分子量 | 336.5 |
| 溶解度 | DMF: >50 mg/ml (per Rao Maddipati),DMSO: >50 mg/ml (per Rao Maddipati),Ethanol: >50 mg/ml (per Rao Maddipati),PBS pH 7.2: >1 mg/ml (from 13(S)-HODE) |
| 储存条件 | Store at -20°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 µM. |
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