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Ac-IEPD-AFC
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ac-IEPD-AFC图片
CAS NO:1135417-31-0
包装:5mg
市场价:2489元

产品介绍
Ac-IEPD-AFC 是颗粒酶 B 的底物。
Cas No.1135417-31-0
化学名4-[(2-acetamido-3-methylpentanoyl)amino]-5-[2-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentanoic acid
Canonical SMILESCCC(C)C(C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)NC2=CC3=C(C=C2)C(=CC(=O)O3)C(F)(F)F)NC(=O)C
分子式C32H38F3N5O11
分子量725.67
溶解度Soluble to 14.51 mg/ml in DMSO
储存条件Desiccate at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ac-IEPD-AFC (IEPD) is a substrate of Granzyme B[1].

The Km of human granzyme B for Ac-IEPD-AFC in granzyme B assay buffer is 585 μM[1].

References:
[1]. Pak SC, et al. SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins. J Biol Chem. 2004 Apr 9;279(15):15448-59.