SR 9186 (ML368) 是一种有效的 CYP3A4 抑制剂，抑制咪达唑仑 → 1'羟基咪达唑仑、睾酮 → 6β-羟基睾酮和长春新碱 → 长春新碱 M1 的 IC50 分别为 9、4 和 38 nM。
| Cas No. | 1361414-26-7 |
| 别名 | ML368 |
| 化学名 | N-(4'-cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-imidazo[4,5-b]pyridin-7-yl)phenyl]-urea |
| Canonical SMILES | O=C(NC1=CC=C(C2=CC=C(C#N)C=C2)C=C1)NC3=CC=C(C4=CC=NC5=C4N=CN5)C=C3 |
| 分子式 | C26H18N6O |
| 分子量 | 430.5 |
| 溶解度 | DMF: Soluble,DMSO: Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SR 9186 |
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