CAS NO: | 1393124-08-7 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | PF-06291874 is a highly potent, non-peptide and orally activeglucagon receptorantagonist. PF-06291874 is under the study for type 2 diabetes mellitus (T2DM)[1][2]. | ||||||||||||||||
体内研究 (In Vivo) | PF-06291874 exposure is approximately dose-proportional with a half-life of ~19.7-22.7 h. PF-06291874 has a fast on and off rate. PF-06291874 is highly bound to human plasma protein, with a mean free fraction of ~0.55%[3]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 503.51 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C26H28F3N3O4 | ||||||||||||||||
CAS 号 | 1393124-08-7 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL(198.61 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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