Melatonin-d7 (N-Acetyl-5-methoxytryptamine-d7) is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activatesmelatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties^[1][2][3]. Melatonin is a novel selectiveATF-6inhibitor and induces human hepatoma cellapoptosisthroughCOX-2downregulation^[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cellsapoptosisvia endoplasmic reticulum stress^[5].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

239.32

C₁₃H₉D₇N₂O₂

615251-68-8

褪黑素 D7

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.