包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Dynorphin A TFA is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A TFA is a highy potentkappaopioid receptor(KOR)agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A TFA can induce neuronal death, and can be used in the research ofneurological disease[1][2]. | ||||||||||||||||
IC50& Target[3] |
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体外研究 (In Vitro) | Dynorphin A TFA (10 μM, 4 h/72 h) increases caspase-3 activity and the level of cytochrome c released from mitochondria in mouse striatal neurons, and induces neuronal death[3]. Cell Viability Assay[3]
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体内研究 (In Vivo) | Dynorphin A TFA (intracerebroventricular injection, 1 μg of 2 μL, a single dose) inhibits vasopressin (VP) release in 24 h water-deprived male rats[5].
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分子量 | 2261.50 | ||||||||||||||||
Formula | C101H156F3N31O25 | ||||||||||||||||
Sequence | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln | ||||||||||||||||
Sequence Shortening | YGGFLRRIRPKLKWDNQ | ||||||||||||||||
中文名称 | 强啡肽A 三氟乙酸 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |