L-谷胱甘肽，氧化（钠盐）是由谷胱甘肽氧化产生的，谷胱甘肽是一种主要的细胞内抗氧化剂和解毒剂。
| Cas No. | 103239-24-3 |
| 别名 | L-氧化型谷胱苷肽钠,L-Glutathione oxidized disodium; GSSG disodium; Oxiglutatione disodium |
| Canonical SMILES | O=C([C@@H](NC(CC[C@@H](C([O-])=O)N)=O)CSSC[C@H](NC(CC[C@@H](C([O-])=O)N)=O)C(NCC(O)=O)=O)NCC(O)=O.[Na+].[Na+] |
| 分子式 | C20H30N6O12S2•2Na |
| 分子量 | 656.6 |
| 溶解度 | PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The ratio of reduced glutathione to oxidized glutathione within cells is often used as an indicator of oxidative stress, with higher concentrations of GSSG predicting increased oxidative stress. |
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