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Antitumor agent-63
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Antitumor agent-63图片
CAS NO:1627600-90-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Antitumor agent-63 (Compound 40),20 (S)-O-linked camptothecin (CPT) 糖复合物,是一种抗肿瘤剂,对正常细胞无毒性。Antitumor agent-63 具有高稳定性和很弱的topoisomerase I (Topo I)直接抑制效果。
生物活性

Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak directtopoisomeraseI (Topo I)inhibition[1].

IC50& Target

Top1

 

体外研究
(In Vitro)

Antitumor agent-63 (Compound 40) shows cytotoxicity activities with IC50values of 1.2, 0.8, 30.5 and >100 μM against HepG2, HCT-116, SW1990 and HEK-293, respectively[1].

分子量

846.79

Formula

C38H46N4O18

CAS 号

1627600-90-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.