CAS NO: | 6151-25-3 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinantSIRT1and aPI3Kinhibitor withIC50s of 2.4 μM, 3.0 μM and 5.4 μM forPI3Kγ,PI3Kδ andPI3Kβ, respectively[1]. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | Quercetin dihydrate is a type of plant-based chemical, or phytochemical, used as an ingredient in supplements, beverages or foods. In several studies, it may have anti-inflammatory and antioxidant properties, and it is being investigated for a wide range of potential health benefits[1].Quercetin dihydrate is a PI3K inhibitor with IC50s of 2.4-5.4 μM. Quercetin dihydrate strongly abrogates PI3K and Src kinases, mildly inhibits Akt1/2, and slightly affected PKC, p38 and ERK1/2[1].Quercetin dihydrate inhibits TNF-induced LDH% release, EC-dependent neutrophils adhesion to bovine pulmonary artery endothelial cells (BPAEC), and BPAEC DNA synthesis and proliferation[2]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 338.27 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C15H14O9 | ||||||||||||||||
CAS 号 | 6151-25-3 | ||||||||||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL(295.62 mM;Need ultrasonic) H2O : 1 mg/mL(2.96 mM;ultrasonic and warming and heat to 80℃) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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