Melatonin-d3 (N-Acetyl-5-methoxytryptamine-d3) is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activatesmelatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties^[1][2][3]. Melatonin is a novel selectiveATF-6inhibitor and induces human hepatoma cellapoptosisthroughCOX-2downregulation^[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cellsapoptosisvia endoplasmic reticulum stress^[5].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

235.30

Solid

C₁₃H₁₃D₃N₂O₂

90735-69-6

褪黑素 D3

Room temperature in continental US; may vary elsewhere.

DMSO : 100 mg/mL(424.99 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。